This how-to guide on drug dosage calculations has been created for student nurses, nurses, pharmacy students, trainee pharmacists and pharmacy technicians. This guide aims to teach you how to calculate a drug dosage from its stock strength.

This learning is divided into three parts.

  • Part 1 will define the two drug dosage calculation formulas that can be used to calculate the required drug dose from stock strength for both oral tablets/capsules and oral liquid medicines.
  • In part 2, you will find drug calculation examples (with detailed steps) on how to calculate the required number of tablets or volume of liquid medicine.
  • Finally, in part 3, you can test what you have learnt by attempting the drug calculation test questions.

Let us get started.

Drug Dosage Calculation Formulas – Part 1

To calculate the number of tablets, use the following drug dosage calculation formula:

Strength required / Stock strength = Number of tablet(s) required

Or another way this drug dosage calculation formula can be expressed is:

What you want / What you’ve got = Number of tablet(s) required

To calculate the volume dose for a liquid medicine, use this drug dosage calculation formula:

(Strength required / Stock strength) × Stock volume = Volume dose required

Or another way this drug dosage calculation formula for liquid medicines can be expressed is:

(What you want / What you’ve got) × What it’s in = Volume dose required

This drug dosage calculation formula can also be used to calculate the volume dose required for injections.

Drug Calculation Examples (With Steps on How to Calculate a Drug Dose) – Part 2

Before working through these drug calculation examples and attempting the drug calculation test questions in the next part, remember to ensure the strength required and stock strength are always in the same units of measure (i.e., both ng, both mcg, both mg or both g). If you are unsure how to convert from one unit of measurement to another, take a look at the conversion between units of measure tables for mass and volume on our sister website; in addition, practice converting from one unit of measurement to another by attempting the units of measurement drug calculations quiz.

How to calculate the number of tablets required

Example:

The doctor prescribes promethazine hydrochloride 20 mg for patient X. The available stock strength you have is 10 mg. How many tablets are required?

Step 1

  • The strength required (what you want): 20 mg
  • Stock strength (what you’ve got): 10 mg in one tablet

Calculating drug dosage from available stock (10 mg promethazine hydrochloride tablet)

Step 2

  • 20 mg / 10 mg = 2 tablets
  • Answer: 2 tablets are required

Example:

The doctor prescribes bendroflumethiazide 7.5 mg on patient X’s drug chart. How many tablets should the nurse administer to patient X if the available stock strength on the ward is 2.5 mg?

Step 1:

  • The strength required: 7.5 mg
  • Stock strength: 2.5 mg

Calculating drug dosage from available stock (2.5 mg bendroflumethiazide tablet)

Step 2

  • 7.5 mg / 2.5 mg = 3 tablets
  • Answer: 3 tablets are required

Example:

The doctor prescribes levothyroxine 0.2 mg on patient X’s drug chart. How many tablets should the nurse administer to patient X if the available stock strength on the ward is 100 mcg.

Step 1:

  • The strength required: 0.2 mg
  • Stock strength: 100 mcg

Calculating drug dosage from available stock (100 mcg levothyroxine tablet)

Step 2:

  • Convert the strength required from mg to mcg so that the units of measurement are the same: 0.2 mg x 1000 = 200 mcg

Step 3:

  • 200 mcg / 100 mcg = 2 tablets
  • Answer: 2 tablets are required

Example:

The doctor prescribes bisoprolol 5 mg on patient X’s drug chart. How many tablets should the nurse administer to patient X if the available stock strength on the ward is 1.25 mg.

Step 1:

  • The strength required: 5 mg
  • Stock strength: 1.25 mg

Calculating drug dosage from available stock (1.25 mg bisoprolol tablet)

Step 2:

  • 5 mg / 1.25 mg = 4 tablets
  • Answer: 4 tablets are required

How to calculate a liquid medication dosage

Example:

A patient requires amisulpride 200 mg. The available stock on the ward is 100 mg/mL (100 mg in 1 mL) oral solution. What volume is required?

Step 1:

  • The strength required (what you want): 200 mg
  • Stock strength (what you’ve got): 100 mg
  • Stock volume (what it’s in): 1 mL

Calculating drug dosage from available stock (100 mg/ml amisulpride oral solution)

Step 2:

  • (200 mg / 100 mg) x 1 mL = 2mL
  • Answer: 2 mL is required

Example:

A patient requires dihydrocodeine 30 mg. The available stock on the ward is 10 mg/5 mL (10 mg in 5 mL) elixir. What volume is required?

Step 1:

  • Strength required: 30 mg
  • Stock strength: 10 mg
  • Stock volume: 5 mL

Calculating drug dosage from available stock (10 mg/5ml dihydrocodeine elixir)

Step 2:

  • (30 mg / 10 mg) x 5 mL = 15 mL
  • Answer: 15 mL is required

Example:

A patient requires ibuprofen 0.3 g. The available stock on the ward is 100 mg/5 mL (100 mg in 5 mL) oral suspension. What volume is required?

Step 1:

  • Strength required: 0.3 g
  • Stock strength: 100 mg
  • Stock volume: 5 mL

Calculating drug dosage from available stock (100 mg/5ml ibuprofen oral suspension)

Step 2:

  • Convert the strength required from g to mg so that the units of measurement are the same: 0.3 g x 1000 = 300 mg

Step 3:

  • (300 mg / 100 mg) x 5 mL = 15 ml
  • Answer: 15 mL is required

Example:

A patient requires morphine sulphate 7.5 mg. The available stock on the ward is 10 mg/5 mL (10 mg in 5 mL) oral solution. What volume is required?

Step 1:

  • Strength required: 7.5 mg
  • Stock strength: 10 mg
  • Stock volume: 5 mL

 

Calculating drug dosage from available stock (10 mg/5ml morphine oral solution)

Step 2:

  • (7.5 mg / 10 mg) x 5 mL = 3.75 mL
  • Answer: 3.75 mL is required

Drug Calculation Test Questions and Answers – Part 3

You can test what you have learned with these drug calculation test questions. There are ten drug dosage calculations to attempt; you will be able to check your answers when you have completed all of the questions.

1. A patient requires atenolol 75 mg. The available stock is 25 mg tablets. How many tablets are required?

 
 
 
 

2. Mrs X is being discharged from the hospital. On her TTO, she has been prescribed ramipril 2.5 mg once daily for 7 days, then 5 mg once daily for 14 days till review with the consultant in clinic. How many tablets should the pharmacy technician dispense if the available stock is 2.5 mg?

 
 
 
 

3. Mr S is prescribed bumetanide oral solution 500 mcg once daily. The doctor has ordered 14 days supply. The available stock is 1 mg/5 mL. What volume should the pharmacist dispense?

 
 
 
 

4. Mr Doe has been prescribed prednisolone 30 mg for twelve days by the respiratory consultant. How many tablets will Mr Doe receive from the pharmacy if the 5 mg strength is dispensed?

 
 
 
 

5. The urologist has prescribed nitrofurantoin 100 mg once daily at night on Mrs P’s drug chart. Mrs P is having trouble swallowing tablets, so the ward pharmacist has stated on the drug chart to give nitrofurantoin oral suspension. What volume should the nurse administer to Mrs P if the available strength is 25 mg/5 mL?

 
 
 
 

6. A patient requires itraconazole 200 mg. The doctor has stated on the drug chart to give only oral suspension. The available stock on the ward is 50 mg/5 mL. What volume is required?

 
 
 
 

7. Mrs J is being discharged from the hospital. On her TTO, she has been prescribed colecalciferol oral solution 800 units once daily. The available stock is 2000 units/mL. The pharmacist has asked the pre-registration pharmacist to also state how many mLs of colecalciferol Mr J should take on the dispensing label. What is the correct dosage on the label?

 
 
 
 

8. Mrs PJ has been prescribed dexamethasone 2 mg daily. The doctor would like you to supply her with 14 days only (the doctor will be reviewing Mrs PJ on day 15). How many tablets should Mrs PJ receive if the available stock at the pharmacy is 500 mcg?

 
 
 
 

9. Patient O has been prescribed hydrocortisone sodium phosphate 300 mg by intravenous injection. The available stock on the ward is 500 mg/5 mL solution for injection. What volume should the nurse administer?

 
 
 
 

10. Patient HO has recently been admitted to the hospital. The patient requires ramipril 10 mg daily. The patient has difficulty swallowing, so the doctor has prescribed an oral solution. The available stock on the ward is 2.5 mg/5 mL. What volume should the nurse give to patient HO?

 
 
 
 

Drug Calculation Tips

  • Make sure the units of measure match
  • Recheck your answer
  • Ask a colleague to calculate the drug dosage as well
  • Does the answer seem to be logical to you?

For further practice on drug dosage calculations, download the following worksheet: calculate the number of tablets to give the patient from a stock strength.